Transepithelial Transport of the Group II Metabotropic Glutamate 2/3 Receptor Agonist (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY354740) and Its Prodrug (1S,2S,5R,6S)-2-[(2′S)-(2′-Amino)propionyl]aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY544344)-Reference-Cited by-同舟云学术

Transepithelial Transport of the Group II Metabotropic Glutamate 2/3 Receptor Agonist (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY354740) and Its Prodrug (1S,2S,5R,6S)-2-[(2′S)-(2′-Amino)propionyl]aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY544344)

Published:2008-10-06 Issue:1 Volume:37 Page:211-220
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Varma Manthena V. S.,Eriksson André H.,Sawada Geri,Pak Youngeen A.,Perkins Everett J.,Zimmerman Cheryl L.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference45 articles.

1. Common characteristics for Na+-dependent sugar transport in Caco-2 cells and human fetal colon

2. Saturable Absorptive Transport of the Hydrophilic Organic Cation Ranitidine in Caco-2 Cells: Role of pH-Dependent Organic Cation Uptake System and P-Glycoprotein

3. Pharmaceutical and pharmacological importance of peptide transporters

4. Bueno AB, de Dios A, Dominguez C, Herin MF, Martin IL, Martin JA, Martinez-Grau MA, Massey SM, Monn JA, Montero C, et al. (2003) inventors

5. Eli Lilly and Company, assignee. Prodrugs of excitatory amino acids. World patent WO/2003/045898. 2003 May 6.

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Amino Acids in the Development of Prodrugs;Molecules;2018-09-11

2. Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery;European Journal of Medicinal Chemistry;2018-08

3. Impact of Influx Transporters on Drug Absorption;Oral Bioavailability Assessment;2017-05-05

4. PepT1, ASBT-Linked Prodrug Strategy to Improve Oral Bioavailability and Tissue Targeting Distribution;Current Drug Metabolism;2015-07-02

5. Amino acids as promoieties in prodrug design and development;Advanced Drug Delivery Reviews;2013-10