Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans-Reference-Cited by-同舟云学术

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Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans

Published:2008-12-15 Issue:3 Volume:37 Page:536-544
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

He Handan,Tran Phi,Yin Hequn,Smith Harold,Batard Yannick,Wang Lai,Einolf Heidi,Gu Helen,Mangold James B.,Fischer Volker,Howard Dan

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference19 articles.

1. Inhibition of Dipeptidyl Peptidase IV Improves Metabolic Control Over a 4-Week Study Period in Type 2 Diabetes

2. Inhibition of dipeptidyl peptidase IV with NVP-DPP728 increases plasma GLP-1 (7-36 amide) concentrations and improves oral glucose tolerance in obese Zucker rats

3. Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo

4. Therapeutic potential of dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes

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3. A systematic review on the clinical pharmacokinetics of vildagliptin in healthy and disease populations;Expert Opinion on Drug Metabolism & Toxicology;2023-11-26

4. Development of Long-Acting Dipeptidyl Peptidase-4 Inhibitors: Structural Evolution and Long-Acting Determinants;Journal of Medicinal Chemistry;2023-08-30

5. Pharmacokinetics and Food Effect Between a 100‐mg Sustained‐Release Tablet and a 50‐mg Immediate‐Release Tablet of Vildagliptin in Healthy Subjects;Clinical Pharmacology in Drug Development;2023-08-07

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