A Phosphomimetic Mutation at Threonine-57 Abolishes Transactivation Activity and Alters Nuclear Localization Pattern of Human Pregnane X Receptor-Reference-Cited by-同舟云学术

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A Phosphomimetic Mutation at Threonine-57 Abolishes Transactivation Activity and Alters Nuclear Localization Pattern of Human Pregnane X Receptor

Published:2009-01-26 Issue:4 Volume:37 Page:719-730
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Pondugula Satyanarayana R.,Brimer-Cline Cynthia,Wu Jing,Schuetz Erin G.,Tyagi Rakesh K.,Chen Taosheng

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference44 articles.

1. In Vivo Activation of Human Pregnane X Receptor Tightens the Blood-Brain Barrier to Methadone through P-Glycoprotein Up-Regulation

2. Ligand-activated Pregnane X Receptor Interferes with HNF-4 Signaling by Targeting a Common Coactivator PGC-1α

3. Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization

4. Human Pregnane X Receptor and Resistance to Chemotherapy in Prostate Cancer

5. The regulation of protein function by multisite phosphorylation – a 25 year update

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4. Target Hopping from Protein Kinases to PXR: Identification of Small-Molecule Protein Kinase Inhibitors as Selective Modulators of Pregnane X Receptor from TüKIC Library;Cells;2022-04-12

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