The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil-Reference-Cited by-同舟云学术

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The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil

Published:2008-02-28 Issue:6 Volume:36 Page:986-990
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Ku Hei-Young,Ahn Hee-Jeong,Seo Kyung-Ah,Kim Hyunmi,Oh Minkyung,Bae Soo Kyung,Shin Jae-Gook,Shon Ji-Hong,Liu Kwang-Hyeon

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference33 articles.

1. Cytochrome P-450 hPCN3, a Novel Cytochrome P-450 IIIA Gene Product That Is Differentially Expressed in Adult Human Liver

2. Vardenafil preclinical trial data: potency, pharmacodynamics, pharmacokinetics, and adverse events

3. Involvement of CYP3A in the Metabolism of Eplerenone in Humans and Dogs: Differential Metabolism by CYP3A4 and CYP3A5

4. Effect of CYP3A5 Expression on Vincristine Metabolism with Human Liver Microsomes

5. Enzymatic characteristics of CYP3A5 and CYP3A4: A comparison ofin vitrokinetic and drug–drug interaction patterns

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