Interspecies Prediction of Human Drug Clearance Based on Scaling Data from One or Two Animal Species-Reference-Cited by-同舟云学术

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Interspecies Prediction of Human Drug Clearance Based on Scaling Data from One or Two Animal Species

Published:2007-07-23 Issue:10 Volume:35 Page:1886-1893
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Tang Huadong,Hussain Azher,Leal Mauricio,Mayersohn Michael,Fluhler Eric

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference21 articles.

1. Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

2. Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

3. Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure

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