Role of CYP3A and CYP2E1 in Alcohol-Mediated Increases in Acetaminophen Hepatotoxicity: Comparison of Wild-Type andCyp2e1(–/

Role of CYP3A and CYP2E1 in Alcohol-Mediated Increases in Acetaminophen Hepatotoxicity: Comparison of Wild-Type andCyp2e1(–/–) Mice

Published:2007-03-28 Issue:7 Volume:35 Page:1223-1231
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Wolf Kristina K.,Wood Sheryl G.,Allard Jenna L.,Hunt Jane A.,Gorman Nadia,Walton-Strong Brooke W.,Szakacs Juliana G.,Duan Su X.,Hao Qin,Court Michael H.,von Moltke Lisa L.,Greenblatt David J.,Kostrubsky Vsevolod,Jeffery Elizabeth H.,Wrighton Steven A.,Gonzalez Frank J.,Sinclair Peter R.,Sinclair Jacqueline F.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference51 articles.

1. Acetaminophen hepatotoxicity

2. In Vitro Metabolism of Styrene to Styrene Oxide in Liver and Lung of Cyp2E1 Knockout Mice

3. Molecular basis for deficient acetaminophen glucuronidation in cats

4. CYP3A-inducing agents and the attenuation of uroporphyrin accumulation and excretion in a rat model of porphyria cutanea tarda

5. The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction.

Cited by 55 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Study on the pharmacokinetics, tissue distribution and excretion of Penthorum chinense Pursh in normal and acute alcoholic liver injury rats using validated UPLC-MS/MS method;Journal of Pharmaceutical and Biomedical Analysis;2024-08

2. Growth Hormone Accelerates Recovery From Acetaminophen-Induced Murine Liver Injury;2023-04-18

3. Hepatic, Extrahepatic and Extracellular Vesicle Cytochrome P450 2E1 in Alcohol and Acetaminophen-Mediated Adverse Interactions and Potential Treatment Options;Cells;2022-08-23

4. Ferulic acid ameliorates acetaminophen‐induced acute liver injury by promoting AMPK ‐mediated protective autophagy;IUBMB Life;2022-05-25

5. Hepatic SIRT6 Modulates Transcriptional Activities of FXR to Alleviate Acetaminophen-induced Hepatotoxicity;Cellular and Molecular Gastroenterology and Hepatology;2022