Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line-Reference-Cited by-同舟云学术

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Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line

Published:2011-05-31 Issue:3 Volume:80 Page:518-528
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Hasegawa Maki,Kapelyukh Yury,Tahara Harunobu,Seibler Jost,Rode Anja,Krueger Sylvia,Lee Dongtao N.,Wolf C. Roland,Scheer Nico

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference47 articles.

1. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11

2. Rifampin drastically reduces plasma concentrations and effects of oral midazolam

3. Pharmacokinetics of single doses of sulphinpyrazone and its major metabolites in plasma and urine;Bradbrook;Br J Clin Pharmacol,1982

4. The pharmacokinetics of pioglitazone in patients with impaired renal function

5. Molecular Mechanisms of Polymorphic CYP3A7 Expression in Adult Human Liver and Intestine

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