A Potent and Selective Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator Improves Movement in Rodent Models of Parkinson's Disease-Reference-Cited by-同舟云学术

A Potent and Selective Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator Improves Movement in Rodent Models of Parkinson's Disease

Published:2012-07-11 Issue:1 Volume:343 Page:167-177
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Le Poul Emmanuel,Boléa Christelle,Girard Francoise,Poli Sonia,Charvin Delphine,Campo Brice,Bortoli Julien,Bessif Abdhelak,Luo Bin,Koser Amy Jo,Hodge Lisa M.,Smith Karen M.,DiLella Anthony G.,Liverton Nigel,Hess Fred,Browne Susan E.,Reynolds Ian J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference37 articles.

1. Pharmacological Activation of mGlu4 Metabotropic Glutamate Receptors Reduces Nigrostriatal Degeneration in Mice Treated with 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine

2. Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism

3. Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia

4. Recent advances in the drug discovery of metabotropic glutamate receptor 4 (mGluR4) activators for the treatment of CNS and non-CNS disorders

5. L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA

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