Impact of Thyroid Cancers on Thyroid Hormones among Patients Attended Tripoli University Hospital

Abstract

Thyroid cancer is one of the most common endocrine system malignancy, accounting for 3.8% of new cancer cases in the US and ranking ninth overall. The number of people diagnosed with thyroid cancer has increased dramatically over the last three decades, indicating the disease's global severity. The purpose of this study was to determine the effect different types of thyroid cancers on thyroid hormones (TSH, T4 and T3). This study was conducted in the Oncology and Endocrinology departments of Tripoli University Hospital (TUH). A total of 70 thyroid cancer patients were targeted, and data was collected using patient record file. TSH, T4 and T3 levels monitored and analyzed in biochemistry laboratory using Cobas e411 Fully Automated Machin. Thyroid cancer struck most females than males. Thyroid cancer incidence has increased among people aged 20 to 40. Most thyroid cancer cases are papillary thyroid carcinoma. Thyroidectomy was done with an 87.14% success rate. The level of TSH hormones increased in thyroid cancer patients. Also, the percentage of T4 hormone levels was mostly increased, whereas thyroid cancer had no proven effect on T3. Papillary thyroid carcinoma was the most common thyroid cancer. There was pronounced effect of thyroid cancer on the TSH and T4 hormone, however T3 hormone remained unchanged.