Impact of insulin pump therapy on glycemic control , and body mass index on Type 1 diabetes mellitus, Tripoli Libya.

Abstract

   Background: Diabetes mellitus is a chronic disease characterized by hyperglycemia that leads after many years  to chronic micro vascular and macro vascular complications .Type 1 diabetes is a life- threatening chronic condition requiring continuous and life-long management that can be stressful for patients and their caregivers. Objectives  is to evaluate the effectiveness of insulin pump therapy on glycemic control , and body mass index in Type 1 DM. Patients and Method: this is retrospectively studied the profiles of 73patients were on insulin pump therapy (28 males and 45 females) attending insulin pump clinic at the National Diabetes& Endocrinology center in Tripoli, Libya, from the period of first January 2014 to last December 2017. Data collected included demographic, clinical,HBA1C level ,and body mass index before, at six months, and after one year of nsulin pump therapy use.Results:61.5% were females ;mean age of patients was 29.08± 8.68 years . The mean duration of diabetes was 11.14±6.54 years. 50.7% of them were students, 83.6% were University students. The most of patients , 91.8%  have no complications of diabetes.  The mean HbA1C values improved from 8.29 ± 1.55 at initiation of the insulin pump  therapy, to 7.27 ± 1.08 at the end of 6 months ,and to 7.35  ± 1.30 at the end of one year, with p value of 0.000. Conclusion: also The Mean body weight has no change  from the start of therapy to the end of one year study (from  25.07 ± 4.54 at start to 25.18 ± 4.74 at end of 6 months to 26 ± 5.14 at end of study with p value 0.000. the impact of insulin pump therapy was positive in maintaining a good glycemic control in most of participants, and unchanged in the body mass index.