Efficacy of Intravesical BCG in Patients with Bladder Cancer in the Tobruk City Population

Abstract

Background: The particular pathophysiology of tumors makes it difficult to treat cancer successfully, The survey's goal was to assess the predictive risk factors for bladder cancer and the efficiency of intravesical BCG as a local example of bacterial cancer therapy in reducing tumor recurrence rates The participants in this study were drawn from Tobruk City and the surrounding area, From January 2022 to June 2022, the study was conducted. Result: Overall, there were 47 patients in our statistical data had 47 patients with bladder cancer and was carried out in Tobruk City, Libya, from January 2022 to June 2022. Only 3.6% of the patients were female, with men making up the majority (93.6%). The study's participants' ages ranged from 2 to 87, with a mean of 59. 18 (38.2%) of the 47 individuals received care, compared to 29 (61.7%) who did not. 17 (94%) of the 18 patients who received BCG were men, and only one patient (0.5%) was a woman. 16 (34.0%) of the 47 patients had tumor recurrences, and 3 passed away. Four (25%) of the patients had conditions related to hypertension, diabetes, or the prostate, and 75% of them received BCG. The remaining 31 patients, with an average age of 50 and 6 (1.9%) undergoing BCG, were all in stable condition. Conclusion: The study found that BCG-immunotherapy effectively reduced NMIBC in 18 out of 47 patients in Tobruk City, with minimal side effects. However, specific risk factors reduced the effectiveness of BCG immunotherapy.