Discovery of a Phosphoinositide 3-Kinase (PI3K) β/δ Inhibitor for the Treatment of Phosphatase and Tensin Homolog (PTEN) Deficient Tumors: Building PI3Kβ Potency in a PI3Kδ-Selective Template by Targeting Nonconserved Asp856
Author:
Affiliation:
1. Gilead Sciences, Inc., 199 E. Blaine Street, Seattle, Washington 98102, United States
2. Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, California 94404, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01821
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