Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance

Author:

Lasalle Manuel1,Hoguet Vanessa1,Hennuyer Nathalie2,Leroux Florence1,Piveteau Catherine1,Belloy Loïc2,Lestavel Sophie2,Vallez Emmanuelle2,Dorchies Emilie2,Duplan Isabelle2,Sevin Emmanuel3,Culot Maxime3,Gosselet Fabien3,Boulahjar Rajaa1,Herledan Adrien1,Staels Bart2,Deprez Benoit1ORCID,Tailleux Anne2,Charton Julie1

Affiliation:

1. Univ. Lille, Inserm, Institut Pasteur de Lille, U1177 - Drugs and Molecules for Living Systems, F-59000 Lille, France

2. Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France

3. Univ. Artois, EA 2465 - Blood-Brain Barrier Laboratory (LBHE), F-62300 Lens, France

Funder

Agence Nationale de la Recherche

Institut National de la Sant? et de la Recherche M?dicale

European Commission

European Regional Development Fund

H2020 European Research Council

Soci?t? d'Acc?l?ration du Transfert de Technologie

Conseil R?gional Nord-Pas de Calais

D?l?gation R?gionale ? la Recherche et ? la Technologie

European Genomic Institute for Diabetes

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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