Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer-Reference-Cited by-同舟云学术

Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer

Published:2016-05-10 Issue:10 Volume:59 Page:4849-4858
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Christiansen Elisabeth¹,Hudson Brian D.²,Hansen Anders Højgaard¹,Milligan Graeme²,Ulven Trond¹

Affiliation:

1. Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

2. Molecular Pharmacology Group, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, United Kingdom

Funder

Teknologi og Produktion, Det Frie Forskningsr??d

Syddansk Universitet

University of Glasgow

Lundbeckfonden

Danish Council for Strategic Research

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00202

Reference40 articles.

1. The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids

2. Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40

3. A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs

4. Gpr40 Is Expressed in Enteroendocrine Cells and Mediates Free Fatty Acid Stimulation of Incretin Secretion

5. The G-Protein−Coupled Receptor GPR40 Directly Mediates Long-Chain Fatty Acid−Induced Secretion of Cholecystokinin

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