Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors-Reference-Cited by-同舟云学术

Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors

Published:2017-01-31 Issue:3 Volume:60 Page:1142-1150
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tso Shih-Chia,Lou Mingliang¹²,Wu Cheng-Yang,Gui Wen-Jun,Chuang Jacinta L.,Morlock Lorraine K.,Williams Noelle S.,Wynn R. Max,Qi Xiangbing¹²,Chuang David T.^ORCID

Affiliation:

1. Chemistry Center, National Institute of Biological Science, Beijing 102206, China

2. Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China

Funder

Welch Foundation

Ministry of Science and Technology of the People's Republic of China

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01540

Reference40 articles.

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3. Regulation of the activity of the pyruvate dehydrogenase complex

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5. Reduced PDK4 Expression Associates with Increased Insulin Sensitivity in Postobese Patients

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