Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P1): Discovery and SAR of a Novel Isoxazole Based Series-Reference-Cited by-同舟云学术

Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P1): Discovery and SAR of a Novel Isoxazole Based Series

Published:2016-03-10 Issue:6 Volume:59 Page:2820-2840
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Watterson Scott H.¹,Guo Junqing¹,Spergel Steve H.¹,Langevine Charles M.¹,Moquin Robert V.¹,Shen Ding Ren¹,Yarde Melissa¹,Cvijic Mary Ellen¹,Banas Dana¹,Liu Richard¹,Suchard Suzanne J.¹,Gillooly Kathleen¹,Taylor Tracy¹,Rex-Rabe Sandra¹,Shuster David J.¹,McIntyre Kim W.¹,Cornelius Georgia¹,D’Arienzo Celia¹,Marino Anthony¹,Balimane Praveen¹,Warrack Bethanne¹,Salter-Cid Luisa¹,McKinnon Murray¹,Barrish Joel C.¹,Carter Percy H.¹,Pitts William J.¹,Xie Jenny¹,Dyckman Alaric J.¹

Affiliation:

1. Bristol-Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00089

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1. Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis

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