Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma-Reference-Cited by-同舟云学术

Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma

Published:2017-02-28 Issue:5 Volume:60 Page:2052-2070
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhou Qingqing,Phoa Athena F.,Abbassi Ramzi H.,Hoque Monira,Reekie Tristan A.,Font Josep S.,Ryan Renae M.^ORCID,Stringer Brett W.¹,Day Bryan W.¹,Johns Terrance G.²,Munoz Lenka^ORCID,Kassiou Michael^ORCID

Affiliation:

1. QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia

2. Oncogenic Signaling Laboratory, Centre for Cancer Research, Hudson Institute of Medical Research, 27 Wright Street, Clayton, Victoria 3168, Australia

Funder

National Health and Medical Research Council

Cancer Institute NSW

Brain Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01840

Reference68 articles.

1. The Protein Interaction Landscape of the Human CMGC Kinase Group