Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents-Reference-Cited by-同舟云学术

Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents

Published:2017-04-24 Issue:9 Volume:60 Page:3755-3775
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Panchaud Philippe¹^ORCID,Bruyère Thierry¹,Blumstein Anne-Catherine¹,Bur Daniel¹,Chambovey Alain¹,Ertel Eric A.¹,Gude Markus¹,Hubschwerlen Christian¹,Jacob Loïc¹,Kimmerlin Thierry¹,Pfeifer Thomas¹,Prade Lars¹,Seiler Peter¹,Ritz Daniel¹,Rueedi Georg¹

Affiliation:

1. Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01834

Reference32 articles.

1. Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance

2. Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

3. In front of and behind the replication fork: bacterial type IIA topoisomerases

4. DNA Topoisomerases

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