Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA-Reference-Cited by-同舟云学术

Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA

Published:2016-12-02 Issue:24 Volume:59 Page:11148-11160
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Abulwerdi Fardokht A.¹²,Shortridge Matthew D.³,Sztuba-Solinska Joanna²,Wilson Robert¹,Le Grice Stuart F. J.²,Varani Gabriele³,Schneekloth John S.¹^ORCID

Affiliation:

1. Chemical Biology Laboratory, National Cancer Institute, 376 Boyles Street, Room 225C, Frederick, Maryland 21702, United States

2. Basic Research Laboratories, National Cancer Institute, Frederick, Maryland 21702, United States

3. Department of Chemistry, University of Washington, Seattle, Washington 98195, United States

Funder

National Cancer Institute

American Cancer Society

National Institutes of Health

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01450

Reference52 articles.

1. Structure based approaches for targeting non-coding RNAs with small molecules

2. Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro.

3. HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure.

4. trans activation of human immunodeficiency virus type 1 is sequence specific for both the single-stranded bulge and loop of the trans-acting-responsive hairpin: a quantitative analysis

5. Tat trans-activates the human immunodeficiency virus through a nascent RNA target

Cited by 72 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of RNA structures and their roles in RNA functions;Nature Reviews Molecular Cell Biology;2024-06-26

2. Nanoarchitectonics-based electrochemical aptasensors for highly efficient exosome detection;Science and Technology of Advanced Materials;2024-05-10

3. Autophagy Deregulation in HIV-1-Infected Cells Increases Extracellular Vesicle Release and Contributes to TLR3 Activation;Viruses;2024-04-20

4. RNA–Small-Molecule Interaction: Challenging the “Undruggable” Tag;Journal of Medicinal Chemistry;2024-03-18

5. HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules;Pharmaceuticals;2023-12-25