Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli-Reference-Cited by-同舟云学术

Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli

Published:2016-04-26 Issue:11 Volume:59 Page:5248-5263
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dennis Matthew L.¹²,Pitcher Noel P.¹,Lee Michael D.¹,DeBono Aaron J.¹,Wang Zhong-Chang¹³,Harjani Jitendra R.¹,Rahmani Raphaël¹,Cleary Ben¹,Peat Thomas S.²,Baell Jonathan B.¹,Swarbrick James D.¹

Affiliation:

1. Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia

2. CSIRO Biosciences Program, Parkville, Victoria 3052, Australia

3. State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, People’s Republic of China

Funder

National Health and Medical Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00002

Reference75 articles.

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3. The Perpetual Challenge of Infectious Diseases

4. Antibiotics: the changing regulatory and pharmaceutical industry paradigm

5. Why is big Pharma getting out of antibacterial drug discovery?

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