Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)-Reference-Cited by-同舟云学术

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)

Published:2017-04-17 Issue:2 Volume:61 Page:482-491
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Schiedel Matthias¹,Herp Daniel¹,Hammelmann Sören¹,Swyter Sören¹,Lehotzky Attila²,Robaa Dina³,Oláh Judit²,Ovádi Judit²,Sippl Wolfgang³,Jung Manfred¹⁴^ORCID

Affiliation:

1. Institute of Pharmaceutical Sciences, University of Freiburg, Albertstraße 25, 79104 Freiburg im Breisgau, Germany

2. Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok körútja 2, H 1117 Budapest, Hungary

3. Institute of Pharmacy, Martin-Luther-University Halle-Wittenberg, Wolfgang-Langenbeck-Straße 4, 06120 Halle (Saale), Germany

4. Freiburg Institute of Advanced Studies (FRIAS), University of Freiburg, Albertstraße 19, 79104 Freiburg im Breisgau, Germany

Funder

Országos Tudományos Kutatási Alapprogramok

Deutsche Forschungsgemeinschaft

European Cooperation in Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01872

Reference72 articles.

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5. Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach

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