Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives-Reference-Cited by-同舟云学术

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Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives

Published:2016-06-06 Issue:12 Volume:59 Page:5706-5720
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Amato Jussara¹,Morigi Rita²,Pagano Bruno¹,Pagano Alessia¹,Ohnmacht Stephan³,De Magis Alessio²,Tiang Yee-Peng²,Capranico Giovanni²,Locatelli Alessandra²,Graziadio Alessandra²,Leoni Alberto²,Rambaldi Mirella²,Novellino Ettore¹,Neidle Stephen³,Randazzo Antonio¹

Affiliation:

1. Department of Pharmacy, University of Naples “Federico II”, via D. Montesano 49, 80131 Napoli, Italy

2. Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy

3. UCL School of Pharmacy, University College London, London WC1N 1AX, U.K.

Funder

Associazione Italiana per la Ricerca sul Cancro

Universita' degli Studi di Napoli Federico II

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00129

Reference39 articles.

1. Non-B DNA conformations as determinants of mutagenesis and human disease

2. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

3. Noncanonical DNA Secondary Structures as Drug Targets: the Prospect of the i-Motif

4. G-quadruplex nucleic acids as therapeutic targets

5. The application of DNA and RNA G-quadruplexes to therapeutic medicines

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