Rational Design of Calpain Inhibitors Based on Calpastatin Peptidomimetics-Reference-Cited by-同舟云学术

Rational Design of Calpain Inhibitors Based on Calpastatin Peptidomimetics

Published:2016-05-18 Issue:11 Volume:59 Page:5403-5415
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Low Kristin E.¹,Ler Spencer²,Chen Kevin J.¹,Campbell Robert L.¹,Hickey Jennifer L.³,Tan Joanne²,Scully Conor C. G.²,Davies Peter L.¹,Yudin Andrei K.²,Zaretsky Serge²

Affiliation:

1. Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, Ontario K7L 3N6, Canada

2. Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada

3. Encycle Therapeutics Inc., 101 College Street, Suite 314, Toronto, Ontario M5G 1L7, Canada

Funder

Canadian Institutes of Health Research

Ontario Genomics Institute

Natural Sciences and Engineering Research Council of Canada

Québec Consortium for Drug Discovery

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00267

Reference67 articles.

1. Calpains — An elaborate proteolytic system

2. Interaction of calpastatin with calpain: a review

3. The Calpain System

4. Calcium Signalling and Disease

5. Calpain Inhibition: A Therapeutic Strategy Targeting Multiple Disease States

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