Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists-Reference-Cited by-同舟云学术

Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists

Published:2016-10-25 Issue:24 Volume:59 Page:11050-11068
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Gang¹,Xue Ding¹,Yang Jun²,Wang Juan²,Liu Xiaohua¹,Huang Wenjing²,Li Jie³,Long Ya-Qiu¹,Tan Wenfu²,Zhang Ao¹³

Affiliation:

1. CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica (SIMM), University of Chinese Academy of Sciences, 555 Zuchongzhi Lu, Building 3, Room 426, Shanghai 201203, China

2. Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China

3. School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China

Funder

Ministry of Science and Technology of the People's Republic of China

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link