Design, Synthesis, and Bioactivation of O-Glycosylated Prodrugs of the Natural Nitric Oxide Precursor Nω-Hydroxy-l-arginine-Reference-Cited by-同舟云学术

Design, Synthesis, and Bioactivation of O-Glycosylated Prodrugs of the Natural Nitric Oxide Precursor Nω-Hydroxy-l-arginine

Published:2016-08-29 Issue:17 Volume:59 Page:8030-8041
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Litty Felix-A.¹,Gudd Julia¹,Girreser Ulrich¹,Clement Bernd¹,Schade Dennis²

Affiliation:

1. Department of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, 24118 Kiel, Germany

2. Department of Chemistry and Chemical Biology, TU Dortmund, Otto-Hahn-Straße 6, 44227 Dortmund, Germany

Funder

Bundesministerium für Wirtschaft und Technologie

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00810

Reference32 articles.

1. Nitric oxide and atherosclerosis: An update

2. Endothelial dysfunction and oxidative stress in arterial hypertension

3. Vascular System: Role of Nitric Oxide in Cardiovascular Diseases

4. The discovery of nitric oxide and its role in vascular biology

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