Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes-Reference-Cited by-同舟云学术

Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes

Published:2016-07-19 Issue:14 Volume:59 Page:6772-6790
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Shiliang¹,Xu Hongling¹,Cui Shichao²,Wu Fangshu¹,Zhang Youli¹,Su Mingbo²,Gong Yinghui¹,Qiu Shaobing¹,Jiao Qian¹,Qin Chun¹,Shan Jiwei¹,Zhang Ming¹,Wang Jiawei¹,Yin Qiao¹,Xu Minghao¹,Liu Xiaofeng¹,Wang Rui¹,Zhu Lili¹,Li Jia²,Xu Yufang¹,Jiang Hualiang²,Zhao Zhenjiang¹,Li Jingya²,Li Honglin¹

Affiliation:

1. State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

2. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences. Shanghai 201203, China

Funder

Ministry of Education of the People's Republic of China

Shanghai Municipal Education Commission

National Natural Science Foundation of China

Ministry of Science and Technology of the People\'s Republic of China

Shanghai Municipal Science and Technology Commission

Fok Ying Tung Education Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine