A Chromogenic and Fluorogenic Peptide Substrate for the Highly Sensitive Detection of Proteases in Biological Matrices
Author:
Affiliation:
1. Anorganisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany
2. Medical Faculty Mannheim, Universität Heidelberg, Maybachstrasse 14, 68169 Mannheim, Germany
Funder
Universität Heidelberg
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00652
Reference37 articles.
1. Future of Protease Activity Assays
2. Lanthanide-based fluorogenic peptide substrate for the highly sensitive detection of thermolysin
3. Allosteric Aptamers Controlling a Signal Amplification Cascade Allow Visual Detection of Molecules at Picomolar Concentrations
4. Probing single-stranded DNA and its biomolecular interactions through direct catalytic activation of factor XII, a protease of the blood coagulation cascade
5. Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
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