Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa-Reference-Cited by-同舟云学术

Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa

Published:2016-07-11 Issue:14 Volume:59 Page:6929-6942
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Heinzl Geoffrey A.¹,Huang Weiliang¹,Yu Wenbo¹,Giardina Bennett J.¹,Zhou Yue¹,MacKerell Alexander D.¹,Wilks Angela¹,Xue Fengtian¹

Affiliation:

1. University of Maryland Computer-Aided Drug Design Center, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, United States

Funder

National Institute of Allergy and Infectious Diseases

American Foundation for Pharmaceutical Education

American Chemical Society

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00757

Reference62 articles.

1. Targeting virulence: a new paradigm for antimicrobial therapy

2. Selectively Guanidinylated Aminoglycosides as Antibiotics

3. Mechanism of action of and resistance to quinolones

4. Multiple Mutations Lead to MexXY-OprM-Dependent Aminoglycoside Resistance in Clinical Strains of Pseudomonas aeruginosa

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