Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug–Drug Interaction Risk Profile-Reference-Cited by-同舟云学术

Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug–Drug Interaction Risk Profile

Published:2022-02-17 Issue:5 Volume:65 Page:3786-3797
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hao Junliang^ORCID,Beck James,Zhou Xin,Lackner Gregory L.,Johnston Richard,Reinhard Matt,Goldsmith Paul,Hollinshead Sean,Dehlinger Veronique,Filla Sandra A.,Wang Xu-shan,Richardson Jeffery^ORCID,Posada Maria,Mohutsky Mike,Schober Doug,Katner Jason S.,Chen Qi,Hu Bingjie,Remick David M.,Coates David A.,Mathes Brian M.,Hawk Mai K.,Svensson Kjell A.,Hembre Erik

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01887

Reference50 articles.

1. The Physiology, Signaling, and Pharmacology of Dopamine Receptors

2. What has been learnt from study of dopamine receptors in Parkinson's disease?

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4. Cloning and expression of human and rat Dt dopamine receptors

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