Neochrysosporazines: Precursor-Directed Biosynthesis Defines a Marine-Derived Fungal Natural Product P-Glycoprotein Inhibitory Pharmacophore
Author:
Affiliation:
1. Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia
Funder
University of Queensland
Institute for Molecular Bioscience, University of Queensland
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01989
Reference11 articles.
1. Lamellarin O, a Pyrrole Alkaloid from an Australian Marine Sponge, Ianthella sp., Reverses BCRP Mediated Drug Resistance in Cancer Cells
2. Lamellarin-S: a New Aromatic Metabolite From an Australian Tunicate, Didemnum sp.
3. Lamellarins O and P: New Aromatic Metabolites From the Australian Marine Sponge Dendrilla cactos
4. Parguerenes: Marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells
5. Nocardioazines: A Novel Bridged Diketopiperazine Scaffold from a Marine-Derived Bacterium Inhibits P-Glycoprotein
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