Design and Development of a Chemical Probe for Pseudokinase Ca2+/calmodulin-Dependent Ser/Thr Kinase

Author:

Russ Nadine12,Schröder Martin12ORCID,Berger Benedict-Tilman12,Mandel Sebastian12,Aydogan Yagmur12,Mauer Sandy3,Pohl Christian3,Drewry David H.45ORCID,Chaikuad Apirat12ORCID,Müller Susanne12ORCID,Knapp Stefan126ORCID

Affiliation:

1. Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences (BMLS), Goethe University Frankfurt am Main, Max-von-Laue-Str. 15, Frankfurt am Main 60438, Germany

2. Institut für Pharmazeutische Chemie, Goethe University Frankfurt am Main, Max-von-Laue-Str. 9, Frankfurt am Main 60438, Germany

3. Buchman Institute for Molecular Life Science and Institute of Biochemistry II, Goethe University Frankfurt am Main, Max-von-Laue-Str. 15, Frankfurt am Main 60438, Germany

4. Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

5. UNC Lineberger Comprehensive Cancer Center, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

6. German Cancer Network (DKTK) and Frankfurt Cancer Institute (FCI), Goethe University Frankfurt am Main, Frankfurt am Main 60438, Germany

Funder

Bayer

Merck KGaA

Deutschen Konsortium f??r Translationale Krebsforschung

Genentech

Pfizer

Genome Canada

Wellcome Trust

AbbVie

Funda????o de Amparo ?? Pesquisa do Estado de S??o Paulo

Boehringer Ingelheim

Merck

Janssen Pharmaceuticals

Eshelman Institute for Innovation, University of North Carolina

Canada Foundation for Innovation

Takeda Pharmaceutical Company

H2020 Health

Frankfurt Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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