Optimization of 4,6-Disubstituted Pyrido[3,2-d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth-Reference-Cited by-同舟云学术

Optimization of 4,6-Disubstituted Pyrido[3,2-d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth

Published:2021-09-13 Issue:18 Volume:64 Page:13719-13735
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Han Yu¹,Zhang Huimin²,Wang Shuxiang¹,Li Bo¹,Xing Kun¹,Shi Yuntao¹,Cao Hongxue¹,Zhang Jian¹,Tong Tong¹,Zang Jie¹,Guan Lihong¹,Gao Xiaoxiao²,Wang Yuetong²,Liu Dan¹,Huang Min¹,Jing Yongkui²^ORCID,Zhao Linxiang¹^ORCID

Affiliation:

1. Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China

2. Liaoning Key Laboratory of Targeting Drugs for Hematological Malignancies, Shenyang Pharmaceutical University, Shenyang, 110016, China

Funder

Samuel Waxman Cancer Research Foundation

Liaoning Revitalization Talents Program

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01084

Reference42 articles.

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