Development of Multifunctional and Orally Active Cyclic Peptide Agonists of Opioid/Neuropeptide FF Receptors that Produce Potent, Long-Lasting, and Peripherally Restricted Antinociception with Diminished Side Effects

Author:

Zhang Mengna1,Xu Biao1,Li Ning1,Zhang Run1,Zhang Qinqin1,Shi Xuerui1,Xu Kangtai2,Xiao Jian1,Chen Dan1,Niu Jiandong1,Shi Yonghang1,Fang Quan1ORCID

Affiliation:

1. Key Laboratory of Preclinical Study for New Drugs of Gansu Province, and Institute of Physiology, School of Basic Medical Sciences, Lanzhou University, 199 Donggang West Road, Lanzhou, Gansu Province 730000, PR China

2. School of Life Sciences, Lanzhou University, 222 Tianshui South Road, Lanzhou, Gansu Province 730000, PR China

Funder

National Natural Science Foundation of China

Gansu Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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