Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design-Reference-Cited by-同舟云学术

Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design

Published:2021-10-14 Issue:20 Volume:64 Page:15334-15348
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Xiao-Ping¹,Harijan Rajesh K.²,Cao Bin³,Kahn Jennifer N.¹,Pierce Michael¹,Tsymbal Anastasiia M.³,Roberge Jacques Y.³^ORCID,Augeri David³,Tumer Nilgun E.¹^ORCID

Affiliation:

1. Department of Plant Biology, Rutgers, The State University of New Jersey, 59 Dudley Road, New Brunswick, New Jersey 08901, United States

2. Department of Biochemistry, Albert Einstein College of Medicine, Jack and Pearl Resnick Campus, 1300 Morris Park Avenue, Bronx, New York 10461, United States

3. Molecular Design and Synthesis Core, Rutgers University Biomolecular Innovations Cores, Office for Research, Rutgers University, 610 Taylor Road, Piscataway, New Jersey 08854, United States

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

National Institutes of Health

NIH Shared Instrumentation Grant

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01370

Reference55 articles.

1. Ricin Poisoning