Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising 18F-Labeled Ligand-Reference-Cited by-同舟云学术

Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising 18F-Labeled Ligand

Published:2021-11-10 Issue:22 Volume:64 Page:16731-16745
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Siméon Fabrice G.¹,Lee Jae-Hoon¹²^ORCID,Morse Cheryl L.¹,Stukes Ian¹,Zoghbi Sami S.¹,Manly Lester S.¹,Liow Jeih-San¹,Gladding Robert L.¹,Dick Rachel M.¹,Yan Xuefeng¹,Taliani Sabrina³^ORCID,Costa Barbara³^ORCID,Martini Claudia³^ORCID,Da Settimo Federico³^ORCID,Castellano Sabrina⁴^ORCID,Innis Robert B.¹,Pike Victor W.¹^ORCID

Affiliation:

1. Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States

2. Department of Nuclear Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 03772, South Korea

3. Department of Pharmacy, University of Pisa, 56126 Pisa, Italy

4. Department of Pharmacy, University of Salerno, 84084 Fisciano, SA, Italy

Funder

Italian Ministero dell???Istruzione, dell???Universita?? e della Ricerca (MIUR), Progetti di Ricerca di Interesse Nazionale

Intramural Research Program, National Institutes of Health (NIMH)

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01562

Reference66 articles.

1. Neuroinflammation in psychiatric disorders: PET imaging and promising new targets

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