Discovery of Novel Inhibitors of Uridine Diphosphate-<i>N</i>-Acetylenolpyruvylglucosamine Reductase (MurB) from <i>Pseudomonas aeruginosa</i>, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients-Reference-Cited by-同舟云学术

Discovery of Novel Inhibitors of Uridine Diphosphate-N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients

Published:2022-01-26 Issue:3 Volume:65 Page:2149-2173
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Acebrón-García-de-Eulate Marta¹^ORCID,Mayol-Llinàs Joan²,Holland Matthew T. O.²,Kim So Yeon¹,Brown Karen P.³⁴,Marchetti Chiara²,Hess Jeannine²^ORCID,Di Pietro Ornella²,Mendes Vitor¹^ORCID,Abell Chris²,Floto R. Andres³⁴,Coyne Anthony G.²^ORCID,Blundell Tom L.¹

Affiliation:

1. Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1GA, U.K.

2. Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.

3. Molecular Immunity Unit, Department of Medicine, MRC Laboratory of Molecular Biology, University of Cambridge, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, U.K.

4. Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, CB23 3RE, UK

Funder

American Leprosy Missions

Schweizerischer Nationalfonds zur F??rderung der Wissenschaftlichen Forschung

Cystic Fibrosis Trust

H2020 Marie Sk??odowska-Curie Actions

Bill and Melinda Gates Foundation

Fondation Botnar

Wellcome Trust

NIHR Cambridge Biomedical Research Centre

Publisher

American Chemical Society (ACS)