Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity-Reference-Cited by-同舟云学术

Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity

Published:2021-10-19 Issue: Volume: Page:
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shen Zhengnan¹²³,Ratia Kiira¹⁴,Cooper Laura¹⁵,Kong Deyu¹²,Lee Hyun¹⁴^ORCID,Kwon Youngjin⁴,Li Yangfeng¹²,Alqarni Saad¹,Huang Fei¹²,Dubrovskyi Oleksii¹²,Rong Lijun⁵,Thatcher Gregory R. J.³^ORCID,Xiong Rui¹²^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States

2. UICentre (Drug Discovery at UIC), University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States

3. Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States

4. Research Resources Center, University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States

5. Department of Microbiology, College of Medicine, University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States

Funder

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01307

Reference51 articles.

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