Pharmacophore-Based Design of Phenyl-[hydroxycyclohexyl] Cycloalkyl-Carboxamide Mitofusin Activators with Improved Neuronal Activity-Reference-Cited by-同舟云学术

Pharmacophore-Based Design of Phenyl-[hydroxycyclohexyl] Cycloalkyl-Carboxamide Mitofusin Activators with Improved Neuronal Activity

Author:

Dang Xiawei¹²^ORCID,Williams Sidney B.³,Devanathan Sriram³,Franco Antonietta²,Fu Lijun⁴,Bernstein Peter R.⁵^ORCID,Walters Daniel⁶,Dorn Gerald W.²³

Affiliation:

1. Department of Cardiology, The First Affiliated Hospital of Xi’an Jiao Tong University, Xi’an, Shaanxi 710061, China

2. Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, United States

3. Mitochondria in Motion, Inc., 4340 Duncan Avenue, Suite 216, St. Louis, Missouri 63110, United States

4. WuXi AppTec Co., Ltd., 666 Gaoxin Road, East Lake High-tech Development Zone, Wuhan, Hubei 430075, China

5. PharmaB LLC, 50 S. 16th Street, Unit 5201, Philadelphia, Pennsylvania 19102, United States

6. Crystal Pharmatech Inc., 3000 Eastpark Blvd., Ste 500B, Cranbury, New Jersey 08512, United States

Funder

U.S. Department of Health and Human Services

China Scholarship Council

Muscular Dystrophy Association

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

Reference31 articles.

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