Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity-Reference-Cited by-同舟云学术

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Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity

Published:2021-09-02 Issue:18 Volume:64 Page:13373-13393
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fallica Antonino N.¹^ORCID,Sorrenti Valeria¹^ORCID,D’Amico Agata G.¹,Salerno Loredana¹^ORCID,Romeo Giuseppe¹^ORCID,Intagliata Sebastiano¹^ORCID,Consoli Valeria¹,Floresta Giuseppe²,Rescifina Antonio¹^ORCID,D’Agata Velia³,Vanella Luca¹^ORCID,Pittalà Valeria¹^ORCID

Affiliation:

1. Department of Drug and Health Sciences, University of Catania, 95125 Catania, Italy

2. Department of Analytics, Environmental & Forensics, King’s College London, Stamford Street, London SE1 9NH, U.K.

3. Sections of Human Anatomy and Histology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy

Funder

Universit?? di Catania

Ministero della Salute

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00633

Reference63 articles.

1. Pharmacological and Clinical Aspects of Heme Oxygenase

2. Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications

3. Heme Oxygenases: Cellular Multifunctional and Protective Molecules against UV-Induced Oxidative Stress

4. Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats

5. Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents

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1. Discovery of a new class of bacterial heme-containing C C cleaving oxygenases;New Biotechnology;2024-11

2. Highly Selective Novel Heme Oxygenase-1 Hits Found by DNA-Encoded Library Machine Learning beyond the DEL Chemical Space;ACS Medicinal Chemistry Letters;2024-08-21

3. Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration;Frontiers in Oncology;2024-07-18

4. Novel Acetamide-Based HO-1 Inhibitor Counteracts Glioblastoma Progression by Interfering with the Hypoxic–Angiogenic Pathway;International Journal of Molecular Sciences;2024-05-15

5. Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer;ACS Medicinal Chemistry Letters;2024-04-30

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