Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of <i>Candidiasis</i>-Reference-Cited by-同舟云学术

Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis

Published:2022-01-31 Issue:3 Volume:65 Page:2656-2674
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wen Wuqiang¹,Cao Hongxuan¹,Huang Yunyuan¹,Tu Jie²,Wan Chen¹,Wan Jian¹^ORCID,Han Xinya¹,Chen Han¹,Liu Jiaqi¹,Rao Li¹^ORCID,Su Chen³,Peng Chao³,Sheng Chunquan²^ORCID,Ren Yanliang¹^ORCID

Affiliation:

1. Key Laboratory of Pesticide & Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China

2. School of Pharmacy, Second Military Medical University, Shanghai 200433, China

3. National Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai 201210, China

Funder

State Administration of Foreign Experts Affairs

Ministry of Education of the People's Republic of China

Central China Normal University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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