Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A4 Mimetics (QNX-sLXms)

Author:

de Gaetano Monica1,Tighe Catherine2,Gahan Kevin2,Zanetti Andrea2,Chen Jianmin3,Newson Justine4,Cacace Antonino1,Marai Mariam1,Gaffney Andrew1,Brennan Eoin1,Kantharidis Phillip5,Cooper Mark E.5,Leroy Xavier6,Perretti Mauro3,Gilroy Derek4,Godson Catherine1,Guiry Patrick J.2ORCID

Affiliation:

1. School of Medicine, Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, Belfield, Dublin D04 N2E5, Ireland

2. Centre for Synthesis and Chemical Biology, School of Chemistry, UCD Conway Institute, University College Dublin, Belfield, Dublin D04 N2E5, Ireland

3. William Harvey Research Institute, Queen Mary University London, London EC1M 6BQ, U.K.

4. Centre for Clinical Pharmacology, University College London, London WC1E 6JF, U.K.

5. Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia

6. Domain Therapeutics SA, 67400 Strasbourg, Illkirch, France

Funder

University College Dublin

Science Foundation Ireland

Irish Research Council

National Health and Medical Research Council

JDRF

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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