Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1-Reference-Cited by-同舟云学术

Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1

Published:2021-11-12 Issue:22 Volume:64 Page:16512-16529
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fiorillo Bianca¹^ORCID,Sepe Valentina¹,Conflitti Paolo²,Roselli Rosalinda¹,Biagioli Michele³,Marchianò Silvia³,De Luca Pasquale⁴,Baronissi Giuliana¹,Rapacciuolo Pasquale¹,Cassiano Chiara¹,Catalanotti Bruno¹,Zampella Angela¹,Limongelli Vittorio¹²^ORCID,Fiorucci Stefano³

Affiliation:

1. Department of Pharmacy, University of Naples “Federico II”, Via D. Montesano, 49, I-80131 Naples, Italy

2. Università della Svizzera italiana (USI), Faculty of Biomedical Sciences, Euler Institute, via G. Buffi 13, CH-6900 Lugano, Switzerland

3. Department of Medicine and Surgery, University of Perugia, Piazza L. Severi 1, 06132 Perugia, Italy

4. Head─Sequencing and Molecular Analyses Center, RIMAR Stazione Zoologica, Villa Comunale, 80121 Naples, Italy

Funder

Ministero dell???Istruzione, dell???Universit?? e della Ricerca

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01078

Reference78 articles.

1. Molecular Cloning and Characterization of a Second Human Cysteinyl Leukotriene Receptor: Discovery of a Subtype Selective Agonist

2. Leukotriene receptors as potential therapeutic targets

3. Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases

4. Cysteinyl Leukotrienes and Their Receptors: Molecular and Functional Characteristics

5. Asthma and leukotrienes: antileukotrienes as novel anti‐asthmatic drugs

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