Structure-Based Optimization of Quinazolines as Cruzain and TbrCATL Inhibitors-Reference-Cited by-同舟云学术

Structure-Based Optimization of Quinazolines as Cruzain and TbrCATL Inhibitors

Published:2021-08-30 Issue:17 Volume:64 Page:13054-13071
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Barbosa da Silva Elany¹²^ORCID,Rocha Débora A.³⁴,Fortes Isadora S.³⁴,Yang Wenqian²,Monti Ludovica²,Siqueira-Neto Jair L.²,Caffrey Conor R.²,McKerrow James²^ORCID,Andrade Saulo F.³⁴⁵^ORCID,Ferreira Rafaela S.¹^ORCID

Affiliation:

1. Biochemistry and Immunology Department, Biological Sciences Institute, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais 31270-901, Brazil

2. Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093-0657, United States

3. Pharmaceutical Synthesis Group (PHARSG), Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul 90040-060, Brazil

4. Pharmaceutical Sciences Graduate Program, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul 90040-060, Brazil

5. Graduate Program in Agricultural and Environmental Microbiology, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul 90040-060, Brazil

Funder

Funda????o de Amparo ?? Pesquisa do Estado de Minas Gerais

National Institute of Allergy and Infectious Diseases

Conselho Nacional de Desenvolvimento Cient??fico e Tecnol??gico

Funda????o de Amparo ?? Pesquisa do Estado do Rio Grande do Sul

Coordena????o de Aperfei??oamento de Pessoal de N??vel Superior

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01151