4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads-Reference-Cited by-同舟云学术

4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads

Published:2021-09-28 Issue:19 Volume:64 Page:14620-14646
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Schäker-Hübner Linda¹,Warstat Robin²,Ahlert Heinz³,Mishra Pankaj⁴,Kraft Fabian B.¹⁵,Schliehe-Diecks Julian³,Schöler Andrea¹,Borkhardt Arndt³,Breit Bernhard²^ORCID,Bhatia Sanil³^ORCID,Hügle Martin⁶,Günther Stefan⁴^ORCID,Hansen Finn K.¹⁵^ORCID

Affiliation:

1. Institut für Wirkstoffentwicklung, Medizinische Fakultät, Universität Leipzig, Brüderstraße 34, D-04103 Leipzig, Germany

2. Institut für Organische Chemie, Albert-Ludwigs-Universität Freiburg, Albertstraße 21, D-79104 Freiburg, Germany

3. Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine University Düsseldorf, Moorenstraße 5, D-40225 Düsseldorf, Germany

4. Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Hermann-Herder-Strasse 9, D-79104 Freiburg, Germany

5. Abteilung für Pharmazeutische und Zellbiologische Chemie, Pharmazeutisches Institut, Universität Bonn, An der Immenburg 4, D-53121 Bonn, Germany

6. Institut für Biochemie, Albert-Ludwigs-Universität Freiburg, Albertstraße 21, D-79104 Freiburg, Germany

Funder

Deutschen Konsortium f??r Translationale Krebsforschung

Deutsche Forschungsgemeinschaft

Heinrich-Heine-Universit??t D??sseldorf

Deutsche Krebshilfe

DSO-Netzwerkverbunde

L??wenstern e.V.

KinderKrebsForschung

Katharina-Hardt-Stiftung

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01119

Reference82 articles.

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