All-d-Enantiomeric Peptide D3 Designed for Alzheimer’s Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-β Precursors-Reference-Cited by-同舟云学术

All-d-Enantiomeric Peptide D3 Designed for Alzheimer’s Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-β Precursors

Published:2021-11-05 Issue:22 Volume:64 Page:16464-16479
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bocharov Eduard V.¹²^ORCID,Gremer Lothar¹³⁴⁵^ORCID,Urban Anatoly S.¹²,Okhrimenko Ivan S.¹^ORCID,Volynsky Pavel E.¹²,Nadezhdin Kirill D.¹²,Bocharova Olga V.¹²,Kornilov Daniil A.¹,Zagryadskaya Yuliya A.¹,Kamynina Anna V.¹⁶,Kuzmichev Pavel K.¹^ORCID,Kutzsche Janine³⁴⁵,Bolakhrif Najoua³⁴⁵,Müller-Schiffmann Andreas⁷,Dencher Norbert A.¹⁸,Arseniev Alexander S.¹²,Efremov Roman G.¹²⁹^ORCID,Gordeliy Valentin I.¹³⁴¹⁰^ORCID,Willbold Dieter¹³⁴⁵^ORCID

Affiliation:

1. Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology (State University), 141701 Dolgoprudny, Russia

2. Department of Structural Biology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia

3. Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, 52425 Jülich, Germany

4. JuStruct: Jülich Center for Structural Biology, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany

5. Institut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany

6. Department of Molecular Neurobiology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia

7. Department of Neuropathology, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany

8. Physical Biochemistry, Chemistry department, Technical University of Darmstadt, 64287 Darmstadt, Germany

9. School of Applied Mathematics, Higher School of Economics, 109028 Moscow, Russia

10. IRIG, Institut de Biologie Structurale (IBS), Université Grenoble Alpes, CEA, CNRS, 38000 Grenoble, France

Funder

Russian Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00632

Reference68 articles.

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