Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2)-Reference-Cited by-同舟云学术

Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2)

Published:2021-08-02 Issue:15 Volume:64 Page:11288-11301
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lee Lung-Chun¹,Peng Yi-Hui¹,Chang Hsin-Huei¹,Hsu Tsu¹,Lu Cheng-Tai¹,Huang Chih-Hsiang¹,Hsueh Ching-Cheng¹,Kung Fang-Chun¹,Kuo Ching-Chuan¹²,Jiaang Weir-Torn¹^ORCID,Wu Su-Ying¹^ORCID

Affiliation:

1. Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC

2. Graduate Institute of Biomedical Sciences, China Medical University, Taichung 406, Taiwan, ROC

Funder

National Health Research Institutes

Ministry of Science and Technology, Taiwan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00663

Reference38 articles.

1. Serine, glycine and one-carbon units: cancer metabolism in full circle