ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties-Reference-Cited by-同舟云学术

ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties

Published:2021-08-30 Issue:17 Volume:64 Page:12917-12937
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pribut Nicole¹^ORCID,D’Erasmo Michael¹,Dasari Madhuri¹,Giesler Kyle E.¹,Iskandar Sabrina¹,Sharma Savita K.¹,Bartsch Perry W.¹,Raghuram Akshay¹,Bushnev Anatoliy¹,Hwang Soyon S.¹,Burton Samantha L.²³,Derdeyn Cynthia A.²³⁴,Basson Adriaan E.⁵,Liotta Dennis C.¹^ORCID,Miller Eric J.¹^ORCID

Affiliation:

1. Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States

2. Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, United States

3. Emory Vaccine Center, Emory University, Atlanta, Georgia 30322, United States

4. Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia 30322, United States

5. HIV Pathogenesis Research Unit, Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg, Gauteng 2193, South Africa

Funder

Center for AIDS Research, Emory University

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01083

Reference65 articles.

1. Metabolism, Biochemical Actions, and Chemical Synthesis of Anticancer Nucleosides, Nucleotides, and Base Analogs

2. Progress towards improving antiviral therapy for hepatitis C with hepatitis C virus polymerase inhibitors. Part I: Nucleoside analogues