Novel Aurora A and Protein Kinase C (α, β1, β2, and θ) Multitarget Inhibitors: Impact of Selenium Atoms on the Potency and Selectivity-Reference-Cited by-同舟云学术

Novel Aurora A and Protein Kinase C (α, β1, β2, and θ) Multitarget Inhibitors: Impact of Selenium Atoms on the Potency and Selectivity

Published:2022-02-15 Issue:4 Volume:65 Page:3134-3150
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bijian Krikor¹,Wernic Dominik¹,Nivedha Anita K.²³,Su Jie¹,Lim Felicia Phei Lin²,Miron Caitlin E.²,Amzil Hind¹,Moitessier Nicolas²^ORCID,Alaoui-Jamali Moulay A.¹^ORCID

Affiliation:

1. Segal Cancer Centre and Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Departments of Medicine and Oncology, McGill University, Montreal, Quebec H3A 0B8, Canada

2. Department of Chemistry, McGill University, Montréal, Québec H3A 0B8, Canada

3. Molecular Forecaster, 7171 rue Frederick Banting, Saint Laurent, Quebec H4S 1Z9, Canada

Funder

Canadian Institutes of Health Research

Fondation du cancer du sein du Québec

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01031