Discovery of (Z)-1-(3-((1H-Pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)-3-(isoxazol-3-yl)urea Derivatives as Novel and Orally Highly Effective CSF-1R Inhibitors for Potential Colorectal Cancer Immunotherapy-Reference-Cited by-同舟云学术

Discovery of (Z)-1-(3-((1H-Pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)-3-(isoxazol-3-yl)urea Derivatives as Novel and Orally Highly Effective CSF-1R Inhibitors for Potential Colorectal Cancer Immunotherapy

Published:2021-11-04 Issue:23 Volume:64 Page:17184-17208
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lv Qi¹,Pan Xiang¹,Wang Dan¹,Rong Quanjin¹,Ma Ben¹,Xie Xiaolong¹,Zhang Yinan¹^ORCID,Wang Junwei¹^ORCID,Hu Lihong¹

Affiliation:

1. Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, P. R. China

Funder

Natural Science Foundation of Jiangsu Province

Government of Jiangsu Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01184

Reference43 articles.

1. Colorectal cancer statistics, 2020