Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment-Reference-Cited by-同舟云学术

Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment

Published:2021-07-05 Issue:14 Volume:64 Page:9989-10000
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ambrosio Francesca Alessandra¹^ORCID,Coricello Adriana¹,Costa Giosuè¹²³^ORCID,Lupia Antonio²³,Micaelli Mariachiara⁴,Marchesi Nicoletta⁵,Sala Federico⁵⁶,Pascale Alessia⁵,Rossi Daniela⁵,Vasile Francesca⁶,Alcaro Stefano¹²³,Collina Simona⁵^ORCID

Affiliation:

1. Dipartimento di Scienze della Salute, Università “Magna Græcia” di Catanzaro, Campus “S. Venuta”, 88100 Catanzaro, Italy

2. Net4Science Academic Spin-Off, Università “Magna Græcia” di Catanzaro, Campus “S. Venuta”, 88100 Catanzaro, Italy

3. Associazione CRISEA—Centro di Ricerca e Servizi Avanzati per l’Innovazione Rurale, Località Condoleo, Belcastro, Catanzaro, Italy

4. CIBIO—Department of Cellular, Computational and Integrative Biology, University of Trento, Via Sommarive 9, Povo, 38123 Trento, Italy

5. Department of Drug Sciences, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy

6. Department of Chemistry, University of Milan, Via Golgi 19, 20133 Milano, Italy

Funder

Ministero dello Sviluppo Economico

European Commission

Ministero dellâ??Istruzione, dellâ??UniversitÃ e della Ricerca

Regione Calabria

European Cooperation in Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00191

Reference60 articles.

1. Protein Kinase C Activation as a Potential Therapeutic Strategy in Alzheimer's Disease: Is there a Role for Embryonic Lethal Abnormal Vision-like Proteins?

2. Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing

3. Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation

4. HuD Promotes BDNF Expression in Brain Neurons via Selective Stabilization of the BDNF Long 3′UTR mRNA

5. Different motif requirements for the localization zipcode element of β-actin mRNA binding by HuD and ZBP1

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